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2 Hypothetically, ibogaine may possibly exert its clinical antidepressant outcome on account of merged direct pharmacological action plus a consciousness-growing working experience. A two-stage phase II randomized medical demo to test ibogaine hydrochloride along with the ibogaine analog 18-methoxycoronaridine for therapy of psychiatric Problems has actually been permitted. Even further trials are warranted to investigate the putative antidepressant result of ibogaine microdosing.

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